Lipum has identified the novel target molecule Bile Salt-Stimulated Lipase (BSSL). Preclinical studies have very successfully verified the concept in several well-established models for autoimmune chronic inflammatory diseases, e.g. Rheumatoid Arthritis (RA). A candidate drug, an optimized monoclonal antibody, is now about to be validated and tested. Also a novel approach to get early proof of concept in man. In parallel production of the biological drug will be established for toxicological and clinical study during year 2020. The Horizon 2020 SME Instrument grant will speed up this development work to the benefit of patients, health care and society.
”We are indeed grateful for being selected by EU considering the tough competition. There is a significant unmet need for the treatment of these diseases and we have first-in-class potential”, says CEO Einar Pontén.